Link between eating uncooked fish and liver cancer in South East Asia

Liver cancer is a malignant neoplastic disease of the liver. Hepatocellular carcinoma (HCC, also called hepatoma) is a primary malignancy (cancer) of the liver. Most cases are secondary to either hepatitis infection (usually hepatitis B or C) or cirrhosis (alcoholism being the most common cause of hepatic cirrhosis).

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Link between eating uncooked fish and liver cancer in South East Asia

Liver Cancer :: Link between eating uncooked fish and liver cancer in South East Asia

An age old preference for eating uncooked fish dishes like ?koi-pla? puts people in SE Asia at risk of ingesting trematodes that can cause a type of liver cancer called cholangiocarcinoma (cancer of the bile ducts), say researchers in this week?s PLoS Medicine.

Banchob Sripa (Khon Kaen University) and colleagues discuss the mechanisms by which the food-borne trematode Opisthorchis viverrini (the SE Asian liver fluke) causes cholangiocarcinoma.

The fluke is endemic to Thailand, Lao People?s Democratic Republic, Vietnam, and Cambodia. In Thailand alone, 6 million people are thought to be infected with the fluke.

Citation: Sripa B, Kaewkes S, Sithithaworn P, Mairiang E, Laha T, et al. (2007) Liver fluke induces cholangiocarcinoma. PLoS Med 4(7): e201.

(Published at www.spiritindia.com on Thursday, July 12, 2007)
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