Health is a unity and harmony within the mind, body and spirit which is unique to each person, and is as defined by that person. The level of wellness or health is, in part, determined by the ability to deal with and defend against stress. Health is determined by physiological, psychological, socio-cultural, spiritual, and developmental stage variables.

GenVec's Malaria Vaccine produces immune response in clinical trial participants

Vaccine :: GenVec's Malaria Vaccine produces immune response in clinical trial participants

Pharmaceutical company GenVec's malaria vaccine candidate is well-tolerated and induces an immune response, according to results from a Phase I/II clinical trial presented by the company at the Malaria Vaccines for the World Conference at the Royal Society of Medicine in London.

The vaccine, produced from GenVec's 293-ORF6 cell line and an associated manufacturing process, is "designed to provide protection against both the liver and blood stages" of the malaria parasite, according to the company.

The clinical trials were sponsored by the National Naval Medical Center and the U.S. Military Malaria Vaccine Program. GenVec said it next plans to assess the safety of the vaccine at a higher dose and then evaluate its efficacy.

PATH, GenVec Vaccine Project

Preclinical trial data involving a separate vaccine candidate from GenVec and the PATH Malaria Vaccine Initiative also were presented at the conference. The data from the vaccine, which includes five antigens from blood and liver stages of the parasite, showed an immune response in animals. "The results from these studies are encouraging and support the use of our adenovector technologies in developing effective malaria vaccines," Joseph Bruder, GenVec's director of vector and vaccine programs, said.

Recently posted related articles on Vaccine :

1. Health :: Number of cases of most vaccine-preventable diseases in US at all-time low
2. Meningitis :: FDA expands age range for use of bacterial meningitis vaccine
3. Malaria :: Malaria vaccine candidate has promising safety, tolerability profile in infants
4. HIV :: Global HIV Vaccine Enterprise names Alan Bernstein as Inaugural Executive Director
5. Pneumonia :: Patients with pneumonia who received pneumococcal vaccine have lower rate of death, ICU admission
6. Vaccine :: Combination vaccine okay for infants, Rochester study shows
7. Vaccine :: UGA vet school receives $1.18 million NIH grant for rabies vaccine investigations
8. Vaccine :: American College of Physicians recommends flu vaccination for health-care workers
9. Flu :: Flu vaccine in painless skin patches under development at Emory, Georgia Tech with NIH grants
10. Anthrax :: HHS purchases additional anthrax vaccine for stockpile