Response to Glucocorticoids Predicts Survival with CNS Lymphoma

Lymphoma :: Response to Glucocorticoids Predicts Survival with CNS Lymphoma

Patients with primary central nervous system (CNS) lymphoma who respond to initial treatment with glucocorticoids appear to have substantially better survival than patients who do not respond. These results were published in the journal Cancer.

To assess whether survival varies by initial response to glucocorticoids, researchers evaluated primary CNS lymphoma patients identified from the Johns Hopkins Cancer Registry. The study was restricted to patients who were diagnosed between 1980 and 2001, were HIV-negative, and had complete medical record information. A total of 57 patients were identified.

The researchers conclude that initial response to treatment with glucocorticoids may provide important information about the prognosis of patients with primary CNS lymphoma.