Specific Gene Mutations Responsible For Congenital Heart Defects

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Specific Gene Mutations Responsible For Congenital Heart Defects

Researchers at UT Southwestern Medical Center at Dallas have discovered a gene critical to the development of the human heart and that mutations in the gene lead to congenital heart defects ? the leading noninfectious cause of death in newborns.

GATA4 is only the second gene to have been identified as a cause of isolated congenital heart disease not associated with medically identified syndromes. The findings will be published in a future edition of the journal Nature and appear online today.

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(Published at www.spiritindia.com on Friday, July 11, 2003)
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