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Endothelial dysfunction with the metabolic syndrome can be reversed by sildenafil
Metabolic Syndrome :: Endothelial dysfunction with the metabolic syndrome can be reversed by sildenafil
Metabolic syndrome is characterized by a number of conditions, including elevated blood pressure, excess body fat around the waist and insulin resistance.Researchers from France explored whether treatment with sildenafil ? a common pharmacologic treatment for ED ? could improve endothelial dysfunction in a rat model.
Researchers administered sildenafil to fructose-fed rats to achieve plasma concentrations known to give efficacy in men and observed endothelial function and oxidative stress in the animals during treatment and one-week after treatment had been stopped. It was observed that chronic sildenafil treatment improved endothelial function and oxidative stress, suggesting that this treatment could be a benefit for cardiovascular indications as well as erectile dysfunction.
(Metabolic Syndrome :: Endothelial dysfunction with the metabolic syndrome can be reversed by sildenafil published at SpiritIndia on Tuesday, May 22, 2007)
Metabolic Syndrome
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