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1. Liver Cancer :: Nexavar approved for patients with inoperable liver cancer
Anticancer drug Nexavar raised survival period in inoperable hepatocellular carcinoma patients suffering from this kind of liver cancer. The U.S. Food and Drug Administration has approved Nexavar (sorafenib) for use in patients with a form of liver cancer known as hepatocellular carcinoma, when the cancer is inoperable. Nexavar was originally approved in 2005 for the treatment of patients with advanced renal cell carcinoma, a form of kidney cancer.

2. Cancer :: Scientific evidence of the significant anti-cancer effect of milk thistle
Recently, scientists demonstrated the anti-cancer effects of silibinin, a major biologically active compound of milk thistle. Being widely used as a folk remedy for liver diseases, milk thistle is safe and well-tolerated, and it protects the liver from drug or alcohol-related injury. Silibinin is highly purified from milk thistle, with a defined chemical structure and molecular weight (C25H22O10, MW: 482.44).

3. Hepatitis B :: Decrease in Liver Transplant in Patients with Hepatitis B
A new Mayo Clinic study found a nationwide decrease in the need for liver transplant in patients with hepatitis B, which coincides with the increasingly widespread use of oral antiviral medications to slow disease progression. The study will be presented this week at the annual meeting of the American Association for the Study of Liver Diseases in Boston.

4. Obesity :: Body-weight regulation scientists give perspective on obesity-related research
When obesity overloads the body with excess nutrients, parts start to fail. Obesity contributes to heart disease, stroke, diabetes, high blood pressure, some cancers, liver disease, immune dysfunction, painful joints, and a host of other problems. With so many parts of the body affected, studies of the health effects of obesity that concentrate on one body organ or system may overlook common underlying events occurring at the cellular level throughout the body.

5. Liver :: Endosonography-guided biliary drainage is useful in cases with failed endoscopic biliary stenting
The role of endosonography (ES) in digestive diseases is expanding gradually from diagnostic applications to therapeutic ones. The feasibility of ES-guided cholangiopancreatography was first reported by Harada et al. (pancreatography) and Wiersema et al. (cholangiography) in 1995 and 1996, respectively. Several reports on the application of ESBD for a therapeutic purpose have been published since 2001. However, there have been no reports as to the influence of this technique on the gut wall, the bile duct, and the intervening tissues.

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